US 9,930,893 B2Granted

Inhibitors of DXP synthase and methods of use thereof

AssigneeThe Johns Hopkins University

InventorsCaren L. Freel Meyers, Francine Morris, Ryan J. Vierling

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Novel inhibitors of DXP synthase and methods of use thereof are disclosed.

Dependent claims

A pharmaceutical composition comprising a compound represented by the formula:

in which
X is phenyl;
R1, independently is absent, or if present, is halo or optionally substituted C1-C4 alkyl;
and,
n is 1;
or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier.

3 more elements

Dependencies are inferred from the claim text.

A01N 57/22
Having phosphorus-to-carbon bonds: containing aromatic radicals
C07F 9/4065
Esters of acids containing the structure -C-P2 or NC-P2,: esters of acids containing the structure -C-P2,
C07F 9/4078
The ester moiety containing a substituent or a structure which is considered as characteristic: esters with unsaturated acyclic alcohols
C07F 9/4087
The ester moiety containing a substituent or a structure which is considered as characteristic: esters with arylalkanols

From the US filing history. Foreign family members aren’t listed.

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