Porous polymer scaffold useful for tissue engineering in stem cell transplantation
AssigneeCouncil of Scientific and Industrial Research
InventorsAmitava Das, Pratyay Basak, Ramasatyaveni Geesala, Nimai Bar, Neha Raghuvir Dhoke, Komal Kaushik
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Abstract
The present invention relates to the synthesis of porous polymer scaffold from polyethyleneglycol-polyurethane having castor oil linkages under controlled conditions and their use as stem cell delivery vehicles thereby accelerating the tissue regeneration process. The present invention further studies the biodegradability, stability and biocompatibility of porous polymer scaffolds in various cell lines and primary bone marrow stem cells. Particularly the present invention further relates to the physio-chemical characterization of the porous polymer scaffolds.
Claims20
A porous polymer scaffold for tissue engineering in stem cell transplantation consisting of a crosslinker, where the crosslinker comprises castor oil, polyether backbone, an isocyanate containing compound, and a secondary component, wherein the scaffold has a pore size that ranges from 50 nm-5 μm.
Dependencies are inferred from the claim text.