Back to results
US 9,913,875 B2Granted
Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making
AssigneesCalifornia Institute of Technology, Indi Molecular, Inc.
InventorsBlake Farrow, James R. Heath, Heather Dawn Agnew
Life of this patent
Estimating the term…
Abstract
The present application provides stable peptide-based Botulinum neurotoxin (BoNT) serotype A capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application further provides methods of manufacturing BoNT serotype A capture agents using iterative on-bead in situ click chemistry.
Claims16
A capture agent comprising an anchor ligand that comprises a cyclic peptide comprising the formula of Dab(DNP)-R-Lys(N3)-T-Dab-Pra-L-SEQ ID NO:3).
Dependencies are inferred from the claim text.