Method for producing fragrant alcohols
AssigneeFirmenich SA
InventorsLaurent Daviet, Letizia Rocci, Michel Schalk
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Abstract
This invention relates generally to methods and compositions for producing a sesquiterpene alcohol comprising contacting a sesquiterpene with a p450 polypeptide with monooxygenase activity.
Claims24
A method of producing one or more sesquiterpene alcohol comprising α-sinensol, β-sinensol, α-santalol, β-santalol, α-trans-bergamotol, epi-β-santalol, lancelol or mixtures thereof, the method comprising contacting one or more of α-farnesene, β-farnesene, α-santalene, β-santalene, α-trans-bergamotene, epi-β-santalene, or β-bisabolene with a polypeptide having a P450 monoxygenase activity;
- wherein the polypeptide having a P450 monoxygenase activity comprises an amino acid sequence having at least 90% sequence identity to SEQ ID NO:
- 71 or SEQ ID NO:
- 73.
An isolated polypeptide having monooxygenase activity comprising the amino acid sequence of SEQ ID NO:
- 73.
Dependencies are inferred from the claim text.