Device and method of extracting high-concentration plasma from whole blood

A kit for extracting high-concentration plasma from whole blood, the kit comprising:

• a first syringe including a first outlet;
• a centrifugation tube configured for direct connection to the first outlet of the first syringe in order to centrifuge whole blood received in the first syringe,
• wherein an inner upper surface of the centrifugation tube has a first curved portion configured to increase a volume of the centrifugation tube for receiving red blood cells and to discharge air from the centrifugation tube during a primary centrifugation, and a portion of the centrifugation tube configured for direction connection to the first outlet of the first syringe, and
• wherein the portion of the centrifugation tube has a first gap serving to prevent red blood cells received in the centrifugation tube from being agglomerated by surface tension and from flowing to outside the centrifugation tube;
• a cap configured for direct connection to the first outlet of the first syringe and configured to re-centrifuge plasma,
• wherein the cap is smaller than the centrifugation tube in length,
• wherein an inner upper surface of the cap has a second curved portion configured to increase a volume of the cap for receiving red blood cells and to discharge air from the cap during a secondary centrifugation, and a portion of the cap configured for direction connection to the first outlet of the first syringe, and
• wherein the portion of the cap has a second gap serving to prevent red blood cells received in the cap from being agglomerated by surface tension and from flowing to outside the cap;
• and
• a membrane filter comprising:
• a cylindrical body including:
• a first inlet configured to receive the first syringe, a second inlet configured to receive a second syringe, and an outlet;
• a hollow cylindrical membrane located within the cylindrical body and substantially coaxial with the cylindrical body, wherein the hollow cylindrical membrane defines an internal cavity configured to pass plasma in a primarily axial direction from the first inlet to the second inlet, and configured to pass plasma in an opposite primarily axial direction from the second inlet to the first inlet;
• and
• a first space formed between the cylindrical body and the hollow cylindrical membrane, wherein the first space is configured to receive water and small components from the internal cavity that are filtered in a substantially radial direction through the hollow cylindrical membrane, thereby increasing a concentration of large components inside the internal cavity each time that plasma is passed from the first inlet to the second inlet or from the second inlet to the first inlet.