Stearic acid derivatives and oleic acid derivatives of multi-arm polyethylene glycol
AssigneeJenkem Technology Co., Ltd. (Tianjin)
InventorsJunye Li, Meina Lin, Xiaomeng Chen
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Abstract
Disclosed are multi-arm polyethylene glycol derivatives having structure of formula I or formula VI. Compared with straight chain polyethylene glycol, multi-arm polyethylene glycol has a plurality of terminal groups, thus has a plurality of introducing points of functional groups and can support a plurality of reactive terminal groups, thereby enabling multi-arm polyethylene glycol to have more flexibility and wider range of application.
Claims16
A multi-arm polyethylene glycol derivative, wherein the multi-arm polyethylene glycol derivative has a structure of general formula I or general formula VI
- wherein:
- PEG is the same or different and is —(CH2CH2O)m—, m is an integer of 3-250;
- l is an integer greater than or equal to 1 and less than or equal to 10;
- X1, X2, X3, and X4 are independently selected from the group consisting of the following groups:
- wherein i is an integer of 0-10;
- F1, F2, F3, and F4 are independently selected from the group consisting of the following groups:
- and, in general formula I at least one of F1, F2, F3, and F4 is
- or in general formula VI at least one of F1, F2, and F4 is
Dependencies are inferred from the claim text.