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US 9,890,118 B2Granted
Prostamides for the treatment of glaucoma and related diseases
AssigneeAllergan, Inc.
InventorsDavid F. Woodward, Robert M. Burk
Life of this patent
Estimating the term…
Abstract
Disclosed herein are compositions comprising an amide related to a prostaglandin and a biogenic amine. Other aspects relate to certain chemical compounds, pharmaceutical compositions, and methods of treating glaucoma.
Claims3
A compound having the formula:
- or a salt thereof,
- wherein:
- the hatched wedge indicates an α configuration and the solid wedge indicates a β configuration;
- the dashed lines indicate the presence or absence of a double bond;
- A and B are both CHOH, or A is CHOH and B is C═O, or B is CHOH and A is C═O;
- R3 is n-butyl or W—Ar;
- Ar is
- W is CH2;
- R4 is hydrogen or C1 to C4 alkyl;
- and
7 more elements
A compound having the formula:
Dependencies are inferred from the claim text.