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US 9,889,207 B2Granted
Pyrrolobenzodiazepines and conjugates thereof
AssigneeMedImmune, LLC
InventorPhilip Wilson Howard
Life of this patent
Estimating the term…
Abstract
A compound which is either A: or B: and salts and solvates thereof, as well as their conjugates with a cell-binding agent.
Claims17
A compound which is selected from the group consisting of A:
- and B:
- where R10 and R11 either
- (a) form a double bond between the carbon and nitrogen atoms to which they are bound;
- or
- (b) are H and ORA respectively, where RA is selected from H and C1-4 alkyl;
- or a pharmaceutically acceptable salt thereof.
3 more elements
A conjugate selected from the group consisting of formula ConjA:
- and ConjB:
Dependencies are inferred from the claim text.