Salts of dasatinib in amorphous form
AssigneeBASF SE
InventorsAndreas Hafner, Fritz Blatter, Martin Szelagiewicz, Bernd Siebenhaar, Tiziana Chiodo, Tobias Hintermann, Beate Salvador, Marcus Vossen
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AssigneeBASF SE
InventorsAndreas Hafner, Fritz Blatter, Martin Szelagiewicz, Bernd Siebenhaar, Tiziana Chiodo, Tobias Hintermann, Beate Salvador, Marcus Vossen
Estimating the term…
The present invention primarily relates to salts of Dasatinib, wherein the salts are in amorphous form. The salts described herein preferably comprise a cation of a compound of formula 1 and an anion of a second compound selected from the group consisting of glutaric acid, nicotinic acid and saccharin. The invention is further related to pharmaceutical compositions comprising such a salt. Furthermore, the invention relates to processes for preparing said salts. The invention also relates to several aspects of using said salt or pharmaceutical composition to treat a disease.
A salt of Dasatinib, wherein the salt is in amorphous form which further contains an organic acid wherein the molar ratio of Dasatinib to the organic acid is in the range of from 0.5 to 2.0 wherein the salt is a salt selected from the group consisting of Dasatinib saccharinate, Dasatinib glutarate, and Dasatinib nicotinate.
Dependencies are inferred from the claim text.