Attenuated vaccinia virus KVAC103 strain
AssigneeKorea Centers for Disease Control and Prevention
InventorsSang Gu Yeo, Ho Sun Son, June Woo Lee, Seung Bin Cha, Sun Hwa Lee, Kwi Sung Park, Sang Won Lee
Life of this patent
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Abstract
The attenuated vaccinia virus strain KVAC103 was obtained by subculturing a vaccinia virus strain 103 times in VERO cells. The attenuated vaccinia virus strain KVAC103 has significantly low toxicity, shows reduced skin lesions, and, at the same time, induces effectively immune responses to poxvirus. Thus, it can be used as a poxvirus vaccine while causing less side effects.
Claims9
The attenuated vaccinia virus strain KVAC103 (Korean Culture Center of Microorganisms [KCCM] accession number KCCM11574P) which has a nucleotide sequence represented by SEQ ID NO:
- 1.
An attenuated vaccinia virus, wherein the genome of said attenuated vaccinia virus comprises a nucleotide deletion from 15,195 to 34,632 and from 139,978 to 142,484 as compared to SEQ ID NO:
- 7.
Dependencies are inferred from the claim text.