# US 9,873,001 B2 · Methods and devices for minimally-invasive delivery of radiation to the eye > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,873,001 B2 - Document ID: US9873001B2 - Status: Granted - Kind: B2 - Application number: 14/486,401 - Filed: 2014-09-15 - Published: 2016-12-29 - Granted: 2018-01-23 - Earliest claimed: 2008-01-07 - Assignees: Salutaris Medical Devices, Inc. - Applicants: Salutaris Medical Devices, Inc. - Inventors: Wendell Lutz; Russell J. Hamilton; Thomas C. Cetas; Laurence J. Marsteller; Timothy Shriver; Samuel S. Hyman - Web page: https://patentgrep.com/patent/US9873001B2 ## CPC - A61N 5/1017: {Treatment of the eye, e.g. for "macular degeneration"} - A61B 1/06: with illuminating arrangements - A61N 5/1007: {Arrangements or means for the introduction of sources into the body} - A61F 9/00: Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand (caps with means for protecting the eyes A42B1/0181; visors for helmets A42B3/22; eye baths A61H35/02; sunglasses or goggles having the same features as spectacles G02C) - A61M 2210/0612: Eyes - A61N 2005/1008: {Apparatus for temporary insertion of sources, e.g. afterloaders} - A61N 2005/1024: {Seeds} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract Methods and devices for minimally-invasive delivery of radiation to the eye (such as the posterior portion of the eye) including cannula systems with multiple treatment positions and/or multiple channels in the distal tip of the cannula systems. The channels can accommodate emanating sources and exposing a target at various treatment positions. The emanating sources may be annulus-shaped. ## Claims ### Claim 1 An emanating source system, the emanating source system comprising an emanating source (401) that emits radiation and an attenuation zone (410) that reduces radiation emitted from the emanating source (401), the attenuation zone (410) is an indentation in a surface of the emanating source (401), wherein radiation is emitted from the emanating source (401) and the attenuation zone (410), and wherein the radiation emitted from the emanating source system provides a substantially uniform dose rate over a diameter of a target, the diameter being equivalent to a diameter of the emanating source. ### Claim 2 (depends on 1) The emanating source system of claim 1, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 10% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 3 (depends on 1) The emanating source system of claim 1, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 20% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 4 (depends on 1) The emanating source system of claim 1, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 50% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 5 (depends on 1) The emanating source system of claim 1, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 80% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 6 (depends on 1) The emanating source system of claim 1, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 90% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 7 (depends on 1) The emanating source system of claim 1, wherein the emanating source is complexed with a carrier. ### Claim 8 An emanating source system comprising an emanating source (401) that emits radiation and an attenuation zone (410) that reduces radiation emitted from the emanating source (401), the attenuation zone (410) is an indentation in a surface of the emanating source (401), wherein radiation is emitted from the emanating source (401) and the attenuation zone (410), wherein the radiation from the emanating source system provides a uniform dose rate over a diameter of a target, the diameter being equivalent to a diameter of the emanating source; and a cannula system (100) comprising a distal portion (110) with a tip (112), wherein the emanating source (401) is disposed at a treatment position (118) in the tip (112). ### Claim 9 (depends on 8) The emanating source system of claim 8, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 10% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 10 (depends on 8) The emanating source system of claim 8, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 20% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 11 (depends on 8) The emanating source system of claim 8, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 50% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 12 (depends on 8) The emanating source system of claim 8, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 80% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410). ### Claim 13 (depends on 8) The emanating source system of claim 8, wherein a radiation dose emitted from the attenuation zone of the emanating source system is about 90% less than a radiation dose emitted from a portion of the emanating source (401) without the attenuation zone (410).