# US 9,872,945 B2 · Blood treatment filter, blood circuit, and blood treatment method

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- Number: US 9,872,945 B2
- Document ID: US9872945B2
- Status: Granted
- Kind: B2
- Application number: 14/416,458
- Filed: 2013-07-25
- Published: 2015-09-24
- Granted: 2018-01-23
- Earliest claimed: 2012-07-25
- Assignees: Asahi Kasei Medical Co., Ltd.
- Applicants: Asahi Kasei Medical Co., Ltd.
- Inventors: Tomohisa Yokomizo
- Web page: https://patentgrep.com/patent/US9872945B2

## CPC

- A61M 1/0281: {Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing}
- A61M 1/0218: {with filters}
- A61M 1/3496: {Plasmapheresis; Leucopheresis; Lymphopheresis (A61M1/3472 takes precedence)}
- A61M 1/3633: {Blood component filters, e.g. leukocyte filters}
- A61M 1/3635: {Constructional details}
- A61M 1/3636: {having a flexible housing}
- A61M 5/36: with means for eliminating or preventing injection or infusion of air into body (dialysis systems, blood oxygenators A61M1/14; haemofiltration equipment A61M1/34; {automatic tube cut-off A61M39/281})
- A61M 2202/0439: White blood cells; Leucocytes
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A blood treatment filter including: a filter container that introduces blood from an inlet into an internal space, and discharges treated blood from an outlet; a filter material that is housed in the filter container to partition the internal space into an inlet side space and an outlet side space, and filters the passing blood to remove a specific component; an inlet port that forms an inlet channel through which the blood flowing from the inlet to the internal space passes; an outlet port that forms an outlet channel through which the blood flowing from the internal space to the outlet passes, wherein the outlet channel has a tapered outlet passage with an inner diameter increasing from the internal space side toward the outlet side.

## Claims

### Claim 1

A blood treatment filter that treats blood introduced from an inlet and discharges the blood from an outlet, the blood treatment filter comprising:
a filter container that introduces the blood from the inlet into an internal space, and discharges the treated blood from the outlet;
a filter material that is housed in the filter container to partition the internal space into an inlet side space and an outlet side space, and filters the passing blood to remove a specific component;
an inlet port that forms a blood introduction passage through which the blood flowing from the inlet to the internal space passes; and
an outlet port that forms a blood lead-out passage through which the blood flowing from the internal space to the outlet passes;
wherein the outlet port has an outlet anterior chamber communicating with the internal space, an outlet connection channel communicating with the outlet and having an outlet tapered portion with first and second ends, and a draw-in opening communicating between the outlet anterior chamber and the outlet connection channel,
the outlet anterior chamber has a floor surface completely surrounding an outer periphery of the draw-in opening, wherein the floor surface is oriented in a plane that is perpendicular to a longitudinal plane in which the filter material is oriented,
the outlet anterior chamber further comprising: a pair of side surfaces facing each other, a dome-shaped surface provided opposite the floor surface, and an end surface spaced apart from the draw-in opening, wherein the dome-shaped surface and the end surface intersect each other in a continuous arc,
the draw-in opening is located at the first end of the outlet tapered portion, the outlet tapered portion having an inner surface with an inner diameter that widens from the first end towards the second end of the outlet tapered portion,
wherein an acute-angled cross section is formed by an intersection of the floor surface of the outlet anterior chamber and the inner surface of the outlet tapered portion when viewed with respect to all cross-sections taken along an imaginary surface including a central axis in a channel direction of the outlet tapered portion, and
wherein the floor surface and the inner surface of the outlet tapered portion, which intersect to form the acute-angled cross section, are configured to enable blood entering the outlet port to form a liquid-tight state within the outlet tapered portion.

### Claim 2 (depends on 1)

The blood treatment filter according to claim 1, wherein the blood introduction passage has an inlet posterior chamber that communicates with the internal space, an inlet connection channel that communicates with the inlet and having an inlet tapered portion, and a communication opening that provides communication between the inlet posterior chamber and the inlet connection channel,
the communication opening is an end point portion of the inlet tapered portion, and
an inner diameter of the inlet tapered portion narrows with distance in a direction towards the communication opening.

### Claim 3 (depends on 2)

The blood treatment filter according to claim 2, wherein a section of an end point portion on an internal space side of the inlet tapered portion has an acute-angled cross section when the inlet port is cut along an imaginary surface including a central axis in a channel direction of the inlet tapered portion.

### Claim 4 (depends on 2)

The blood treatment filter according to claim 2, wherein the inlet posterior chamber has a ceiling surface, and
the communication opening is provided in a part of the ceiling surface of the inlet posterior chamber.

### Claim 5 (depends on 4)

The blood treatment filter according to claim 4, wherein the inlet posterior chamber further comprises a pair of side surfaces facing each other with the communication opening therebetween, and
an inner diameter of the communication opening is smaller than a separation distance between the pair of side surfaces.

### Claim 6 (depends on 5)

The blood treatment filter according to claim 5, wherein the communication opening is provided closer to the internal space side than an inlet deepest portion most distant from the internal space in the inlet posterior chamber.

### Claim 7 (depends on 1)

A blood circuit comprising:
the blood treatment filter according to claim 1;
a storage bag that stores blood;
a collection bag that stores blood after treatment with the blood treatment filter;
an inlet side circuit portion that connects the storage bag and the inlet port of the blood treatment filter; and
an outlet side circuit portion that connects the outlet port of the blood treatment filter and the collection bag.

### Claim 8 (depends on 1)

A blood treatment method that uses the blood treatment filter according to claim 1 and filters blood by gravity.