US 9,872,893 B2Granted

Endolysins active against Staphylococcus bacteria, pharmaceutical compositions, and methods relating thereto

AssigneeUniversity of Maryland, College Park

InventorDaniel C. Nelson

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Abstract

The present invention relates to methods of treating or preventing a bacterial disease or infection, antibacterial compositions, and antibacterial surfaces, including isolated endolysin polypeptides from bacteriophage GRCS.

Claims8

Dependent claims

A method of treating a Staphylococcal infection in a subject comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising the amino acid sequence of SEQ ID NO:

Dependencies are inferred from the claim text.

Facts

Application: 14/794,186Filed 8 Jul 2015 · us provisional application
Priority: 10 Jul 2014
Published: US 2016/0038572 A111 Feb 2016
Granted: 23 Jan 2018
Term ends: Not estimatedThe source records don’t support an estimate.

Classification10 codes

A61K 38/47
Hydrolases: acting on glycosyl compounds , e.g. cellulases, lactases
A61K 38/12
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: cyclic peptides , e.g. bacitracins; Polymyxins; Gramicidins…
A61K 38/14
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: peptides containing saccharide radicals; Derivatives…
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…

Family

Application62/023,096Us provisional application · filed 10 Jul 2014
US 2016/0038572 A1Pre-grant publication · published 11 Feb 2016
US 9,872,893 B2This patent

From the US filing history. Foreign family members aren’t listed.

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