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US 9,868,990 B2Granted
Compositions and methods for detecting and treating neurological conditions
AssigneesThe Regents of the University of Michigan, The Trustees of the University of Pennsylvania
InventorsJohn K. Fink, Shirley Rainier, Robert D. Nicholls, Jinghua Chai
Life of this patent
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Abstract
The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
Claims6
A nucleic acid molecule consisting of at least 30 contiguous nucleotides of SEQ ID NO:
- 2, wherein the nucleic acid includes position 134 of SEQ ID NO:
- 2 and wherein said nucleic acid is detectably labeled with a reporter molecule, wherein the reporter molecule is enzymatic, fluorescent, radioactive, and/or luminescent.
Dependencies are inferred from the claim text.