Sfrp5-derived peptide fragment and cosmetic composition for skin whitening containing same
AssigneesKnu-Industry Cooperation Foundation, Supadelixir Inc.
InventorsJang-Hee Hahn, Dong-Young Lim
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Abstract
Provided is a peptide fragment derived from secreted frizzled protein 5 (Sfrp5), i.e., a peptide fragment selected from the group consisting of the peptides as set forth in SEQ ID NOs: 1 to 9 and a cosmetic composition for skin-whitening and/or inhibiting skin pigmentation comprising the same as an active ingredient. The peptide fragment inhibits melanin formation in melanocytes, thereby having an inhibitory activity against skin pigmentation. Further provided is a reagent for researching or analyzing the inhibition of Wnt signaling pathways comprising the peptide fragment.
Claims3
A method for skin-whitening, comprising administering to a subject in need thereof an effective amount of a secreted frizzled protein 5 (Sfrp5)-derived peptide fragment selected from the group consisting of the peptides as set forth in SEQ ID NOs:
- 1 to 9.
A method for inhibiting skin pigmentation, comprising administering to a subject in need thereof an effective amount of a secreted frizzled protein 5 (Sfrp5)-derived peptide fragment selected from the group consisting of the peptides as set forth in SEQ ID NOs:
- 1 to 9.
Dependencies are inferred from the claim text.