US 9,868,728 B2Granted

Quinazoline derivatives, compositions, and uses related thereto

AssigneeEmory University

InventorsJohn David Lambeth, Thota Ganesh, Susan M. Smith, Aiming Sun

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Abstract

The invention relates to quinazoline derivatives, compositions, and methods related thereto. In certain embodiments, the invention relates to inhibitors of NADPH-oxidase.

Claims4

Dependent claims

A pharmaceutical formulation comprising 6-chloro-3-(3-(dimethylamino)propyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one or salt thereof and a pharmaceutically acceptable carrier.

Dependencies are inferred from the claim text.

Facts

Application: 13/876,869Filed 25 Oct 2011 · us provisional application
Priority: 29 Oct 2010
Published: US 2013/0225612 A129 Aug 2013
Granted: 16 Jan 2018
Term ends: Not estimatedThe source records don’t support an estimate.

Classification17 codes

C07D 417/12
Containing two hetero rings: linked by a chain containing hetero atoms as chain links
A01N 1/126
Preservation or perfusion media: physiologically active agents, e.g. antioxidants or nutrients
A61K 8/4953
With more than one nitrogen as the only hetero atom: containing pyrimidine ring derivatives, e.g. minoxidil
A61K 31/517
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim: ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

Family

Application61/407,925Us provisional application · filed 29 Oct 2010
US 2013/0225612 A1Pre-grant publication · published 29 Aug 2013
US 9,868,728 B2This patent

From the US filing history. Foreign family members aren’t listed.

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