Carrier for blood component adsorption and blood component adsorption column
AssigneeToray Industries, Inc.
InventorsNaotoshi Tomita, Yoshiyuki Ueno, Kazuhiro Tanahashi
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Abstract
A carrier for blood component adsorption enables selective and efficient adsorption removal of granulocytes and monocytes and, at the same time, enables adsorption removal of inflammatory cytokines. The carrier for blood component adsorption includes a water-insoluble carrier having a surface to which a functional group(s) containing a silyl group and an amino group is/are introduced.
Claims22
A carrier for blood component adsorption comprising a water-insoluble carrier having a surface to which a functional group(s) containing a silyl group and an amino group is/are introduced, wherein said silyl group is terminally positioned in both the functional group and the water-insoluble carrier, wherein said water-insoluble carrier is polyolefin, fluorinated polymer, polysulfone-based polymer, polyetherimide, polyimide, polyamide, polyether, polyphenylene sulfide, polystyrene, acrylic polymer or a blend or alloy thereof, and wherein the water-insoluble carrier is functionalized with a reactive functional group(s) reactive with said amino group before introducing the functional group(s) containing the silyl group and the amino group to the carrier, wherein the reactive functional group(s) is selected from the group consisting of halomethyl group, haloacetyl group, haloacetamidomethyl group and halogenated alkyl group, epoxide group, isocyanate group, thioisocyanate group and acid anhydride group.
Dependencies are inferred from the claim text.