Complex in which anti-cotinine antibody is bound to conjugate of cotinine and binding substance, and use thereof
AssigneeSnu R&Db Foundation
InventorsJunho Chung, Sunyoung Park, Do Been Hwang, Hwa Kyoung Lee
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Abstract
The present invention relates to a complex in which an anti-cotinine antibody is bound to a conjugate of a binding material and cotinine, and a use of the complex. The complex according to the present invention may be used as an analysis tool in an in vitro biological assay method, and may retain the specific reactivity and the biological function of the binding material, and the capabilities of inducing complement-mediated cell cytotoxicity (CDC) and antibody-dependent cell cytotoxicity (ADCC) and a prolonged in vivo half-life, which are intrinsic characteristics of an antibody.
Claims4
A complex in which an anti-cotinine antibody is bound to a conjugate of cotinine and a binding material,
- wherein the binding material is selected from the group consisting of a peptide, an aptamer, an antibody, and a hormone, and
- wherein the binding material is linked to the cotinine via a PEG linker or an amino C6 linker.
Dependencies are inferred from the claim text.