Pharmaceutical composition for treating or preventing corneal wound comprising thymosin β4 and citric acid
AssigneeG-Treebnt Co., Ltd.
InventorsSin Wook Kang, Kyoungsun Kim, Ji Hye Sung
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Abstract
The present invention relates to a composition for the treatment or prevention of a corneal injury, which comprises thymosin β4, and citric acid or its salt as active ingredients. The composition may further comprise at least one organic acid selected from acetic acid, ascorbic acid or salts thereof. The composition can maintain or increase the activity of thymosin β4 conventionally used to effectively treat wounds on the cornea, and thus, is useful as an ophthalmic formulation for treating the corneal injury.
Claims12
A method for the treatment of a corneal injury, comprising administering (i) a first composition comprising thymosin β4 as an active ingredient and (ii) a second composition comprising citric acid or its salt, as an active ingredient, to a subject in need thereof, wherein an amount of the thymosin β4 in the first composition ranges from 0.05 to 0.5% (w/v) based on the total volume of the first composition, and an amount of the citric acid or its salt in the second composition ranges from 1.0 to 10.0% (w/v) based on the total volume of the second composition.
Dependencies are inferred from the claim text.