Method of using mitotically inactivated stem cells for damaged tissue repair
OwnerRichard Burtinventor
Life of this patent
Estimating the term…
Abstract
The present invention is directed to the use of mitotically and/or lethally inactivated stem cells for the repair of damaged organs and/or tissues. Stem cells are mitotically and/or lethally inactivated and transplanted into damaged tissue. Any form of ex vivo inactivation of stem cells may be used such that the stem cells cannot undergo mitosis or cell division before in vivo application. Mitotically and/or lethally inactivated stem may be used to ameliorate numerous disease, injury, traumatic, ischemic, aging, and/or degenerative conditions in different types of organs and/or tissues.
Claims6
A method for treating whole body radiation injury in a mammal, the method comprising:
- intravenously injecting the mammal with an effective amount of lethally inactivated mammalian pluripotent stem cells that cannot undergo mitosis, the lethally inactivated mammalian stem cells being of the same species as the mammal undergoing treatment, wherein the effective amount provides the treated mammal with an improved rate of survival after radiation injury.
A method for treating whole body radiation injury in a mammal, the method comprising:
- treating mammalian pluripotent stem cells in a manner effective to provide lethally inactivated mammalian pluripotent stem cells that cannot undergo mitosis;
- and
- intravenously injecting the mammal with an effective amount of the lethally inactivated mammalian pluripotent stem cells, the lethally inactivated mammalian pluripotent stem cells being of the same species as the mammal undergoing treatment, wherein the effective amount provides the treated mammal with an improved rate of survival after radiation injury.
Dependencies are inferred from the claim text.