Compositions and methods for treating hyperkalemia
AssigneeArdelyx, Inc.
InventorsDominique Charmot, James P. Davidson, Fangling Lin, Jeffrey W. Jacobs, Natalia Blinova, Eric Labonte, Ingrid Langsetmo, Robert C. Blanks
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Abstract
The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
Claims26
A calcium salt of a crosslinked potassium binding polymer having the following structure:
- wherein the ratio of “m” and “n” provides a polymer having 1.0% to 1.9% cross-linking.
A calcium salt of a crosslinked potassium binding polystyrene sulfonate divinylbenzene polymer characterized by a crosslinking of 1.0% to 1.9%.
Dependencies are inferred from the claim text.