Absorbent ingestible agents and associated methods of manufacture and use
AssigneeWellosophy Corporation
InventorsRichard Davis, Lior Sher
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Abstract
Appetite suppression and weight management achieved through pre-meal ingestion of temporary gastric bulking agents in the form of superabsorbent polymer hydrogels (SAPHs) selected from among a group consisting of crosslinked polycarboxylic acid moieties is described. The preferred compositions and manufacturing methods of ultrapure preparations of ingestible forms; as well as the preferred methods of use, dosage and administration; distribution and delivery of SAPH materials are also described.
Claims10
A method of modulating appetite in an individual comprising administering an effective amount of a gastric bulking composition for oral delivery in a unitary dosage form prior to a meal, wherein the composition is effective in promoting early satiety and the composition comprises at least one of a crosslinked polycarboxylate homopolymer, a crosslinked polycarboxylate copolymer or combination thereof;
- and a pharmaceutically acceptable excipient, wherein:
- from about 5% by weight to about 20% by weight of the total amount of the composition is retained on a 500 micron mesh;
- from about 25% by weight to about 90% by weight of the total amount of the composition is retained on a 180 micron mesh;
- and
- from about 1% by weight to about 15% by weight of the total amount of the composition is retained on a 106 micron mesh.
Dependencies are inferred from the claim text.