Compositions for treating neurological disorders
AssigneePharnext
InventorsDaniel Cohen, Ilya Chumakov, Serguei Nabirochkin, Emmanuel Vial, Mickaël Guedj
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Abstract
The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorders, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury.
Claims9
A composition comprising a pharmaceutically acceptable carrier or excipient and a synergistic combination of torasemide, or a salt, or sustained release formulation thereof and a compound selected from aminocaproic acid, eplerenone and terbinafine or salt(s), or sustained release formulation(s) thereof, wherein torasemide and the are each provided in a sub-optimal dose.
Dependencies are inferred from the claim text.