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US 9,867,835 B2Granted
Methods and compositions for treating and preventing viral infections
AssigneeEnterin Laboratories, Inc.
InventorMichael Zasloff
Life of this patent
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Abstract
A method of treating or preventing a systemic viral infection in a mammal by administering a pharmaceutically acceptable composition selected from the group consisting of squalamine, an active isomer thereof, and an active analogue thereof, via a dosing regimen that delivers effective antiviral concentrations of squalamine. Also compositions for achieving the systemic antiviral effect.
Claims20
An in vivo method of treating a viral infection in a mammal comprising administering a composition comprising:
- (a) a pharmaceutically acceptable grade of squalamine or a pharmaceutically acceptable salt thereof in an amount sufficient to produce an antiviral effect, and
- (b) at least one pharmaceutically acceptable carrier,
- wherein the viral infection is caused by a virus selected from the group consisting of Cytomegalovirus, Herpes Simplex virus, Herpes Zoster virus, Orthomyxoviridae, and Picomaviridae, and
- wherein the composition is systemically administered intravenously, subcutaneously, intramuscularly, orally, or by inhalation.
1 more element
Dependencies are inferred from the claim text.