# US 9,867,788 B2 · Multi-chamber cellular mixing and delivery system and method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,867,788 B2 - Document ID: US9867788B2 - Status: Granted - Kind: B2 - Application number: 13/382,703 - Filed: 2010-07-09 - Published: 2012-04-26 - Granted: 2018-01-16 - Earliest claimed: 2009-07-09 - Assignees: Boston Scientific Scimed, Inc. - Applicants: Tania M. Schroeder; Natalie Ann Sautner - Inventors: Tania M. Schroeder; Natalie Ann Sautner - Web page: https://patentgrep.com/patent/US9867788B2 ## CPC - A61K 31/00: Medicinal preparations containing organic active ingredients - A61M 5/19: having more than one chamber - A61M 2210/167: Penis - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A multi-chamber injection and treatment system includes a first chamber, a second chamber, a mixing element, and a needle portion. The first chamber is generally adapted to receive and advance various cells, while the second chamber is adapted to receive and advance adipose tissue, and can blend or reduce the size of the adipose tissue. The mixing element combines the constituents of the chambers and is in communication with the needle portion for driving the cellular mixture into a target tissue site, such as the mid-corpora of the male penis. ## Claims ### Claim 1 A multi-chamber mixing and injection system, the system comprising: a first chamber adapted to receive a cellular matter; a second chamber adapted to receive adipose tissue; a tissue reduction element in fluid communication with the second chamber, the tissue reduction element including a blade assembly moveable to produce a reduced adipose tissue and push the reduced adipose tissue distally; an mixing element in fluid communication with a distal outlet port of the first chamber and a distal outlet port of the second chamber, the mixing element including a freely rotatable member to mix the cellular matter and the reduced adipose tissue into a cellular mixture; and an injection element on fluid communication with the mixing element. ### Claim 2 (depends on 1) The system of claim 1, further comprising a filter element adapted to receive the reduced adipose tissue for filtering adipose tissue of a predetermined size. ### Claim 3 (depends on 2) The system of claim 2, wherein the filter element excludes reduced adipose tissue particles greater than about 1 mm in size. ### Claim 4 (depends on 1) The system of claim 1, wherein the injection element is a needle. ### Claim 5 (depends on 4) The system of claim 4, wherein the needle is of a predetermined length to promote insertion into the mid-corpora of a male penis. ### Claim 6 (depends on 5) The system of claim 5, further comprising an adjustable stop element operably coupled to the needle for adjusting an insertion length of the needle. ### Claim 7 (depends on 1) The system of claim 1, wherein the blade assembly comprises a plurality of rotating blades. ### Claim 8 (depends on 1) The system of claim 1, wherein the blade assembly is drivable along a plurality of the second chamber. ### Claim 9 (depends on 1) The system of claim 1, wherein the blade assembly is operably coupled to a distal end of a rotatable drive shaft. ### Claim 10 (depends on 9) The system of claim 9, wherein a proximal end of the drive shaft is operably coupled to a drive motor for rotating the drive shaft. ### Claim 11 (depends on 9) The system of claim 9, wherein a proximal end of the drive shaft is operably coupled to a handle member for manual rotation of the drive shaft. ### Claim 12 (depends on 1) The system of claim 1, further comprising a first plunger device moveable to push the cellular matter distally through the first chamber. ### Claim 13 (depends on 12) The system of claim 12, wherein the plunger device and the blade assembly are independently operable. ### Claim 14 (depends on 12) The system of claim 12, wherein the plunger device and the blade assembly are operable to push the cellular matter and the reduced adipose tissue simultaneously. ### Claim 15 (depends on 1) The system of claim 1, wherein the freely rotatable member of the mixing element comprises a rotatable propeller member. ### Claim 16 (depends on 1) The system of claim 1, wherein the freely rotatable member of the mixing element comprises a rotatable paddle member. ### Claim 17 (depends on 1) The system of claim 1, wherein the mixing element comprises a first spray nozzle for creating a stream of the cellular matter and a second spray nozzle for creating a stream of the reduced adipose tissue. ### Claim 18 A method of mixing a cellular mixture, the method comprising: filling a first chamber with a cellular matter and a second chamber with an adipose tissue, the second chamber including a tissue reduction element in fluid communication therewith, the tissue reduction element including a blade assembly; passing the cellular matter distally through the first chamber; moving the blade assembly to produce a reduced adipose tissue and push the reduced adipose tissue distally through the second chamber; and operating a freely rotatable member of a mixing element in fluid communication with the first and second chambers to mix the cellular matter and the reduced adipose tissue. ### Claim 19 (depends on 18) The method of claim 18, wherein moving the blade assembly comprises driving the blade assembly along a plurality of threads within the second chamber. ### Claim 20 A multi-chamber mixing and injection system, comprising: a first chamber adapted to receive a cellular matter, the first chamber having a first longitudinal axis; a second chamber adapted to receive an adipose tissue, the second chamber having a second longitudinal axis; a plunger device for advancing the cellular matte through the first chamber along the first longitudinal axis; a tissue reduction element in fluid communication with the second chamber, the tissue reduction element including a blade assembly moveable to produce a reduced adipose tissue and push the reduced adipose tissue through the second chamber along the second longitudinal axis; a mixing element in fluid communication with the first chamber and the second chamber, the mixing element including a freely rotatable member to mix the cellular matter and the reduced adipose tissue into a cellular mixture; and an injection element in fluid communication with the mixing element. ### Claim 21 (depends on 20) The system of claim 20, wherein the first longitudinal axis is parallel with the second longitudinal axis.