US 9,867,782 B2 · Spray-dried blood products and methods of making same

Abstract

The present invention is directed to a method of preparing dehydrated blood products, comprising the steps of: (a) providing a hydrated blood product; (b) spray-drying the hydrated blood product to produce a dehydrated blood product, as well as dehydrated blood products made by the method. The present invention is directed to a method of treating a patient suffering from a blood-related disorder, comprising the steps of: (a) rehydrating a therapeutic amount of the dehydrated blood products to produce a rehydrated therapeutic composition; and (b) administering the rehydrated therapeutic composition to the patient. The present invention is directed to a bandage or surgical aid comprising the dehydrated blood products described above.

Claims6

Dependent claims

A method of preparing dehydrated plasma, comprising the steps of:

a. providing hydrated plasma having a first level of activities of clotting factors;
b. measuring said first level of activities of clotting factors;
c. spray-drying said hydrated plasma at a temperature between about 110° C. to about 140° C. to produce dehydrated plasma, wherein said activities of clotting factors are preserved;
d. measuring a second level of activities of said clotting factors after said spray-drying;
and
e. rehydrating said dehydrated plasma comprising said second level of activities of clotting factors that are essentially the same as said first level of clotting factors.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application

13/262,931Filed 6 Apr 2010 · us provisional application

Priority

9 Apr 2009

Published

US 2012/0027867 A12 Feb 2012

Granted

16 Jan 2018

Term ends

Not estimatedThe source records don’t support an estimate.

Classification18 codes

A61K 9/1688
Processes: resulting in pure drug agglomerate optionally containing up to 5% of excipient
A61F 13/00063
Accessories for dressings: comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
A61K 9/0026
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in…
A61K 35/16
Blood; Artificial blood: blood plasma; Blood serum

Spray-dried blood products and methods of making same

Life of this patent

Spray-dried blood products and methods of making same

Life of this patent

Abstract

Claims6