US 9,867,589 B2Granted

System and method to achieve rapid quantitative dynamic molecular imaging scans

AssigneeBayer HealthCare LLC

InventorArthur E. Uber, III

Life of this patent

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Abstract

Methods and systems for controlled administration of a tracer and quantification of uptake of the tracer by a target organ are described. The method includes administering a tracer to a patient and imaging at least two regions of the patient's body that cannot be imaged simultaneously. An input function for the tracer can be determined by imaging a first region of the patient's body during selected times, and using an injector to administer the tracer in a manner that accurately estimates the input function when this first region is not being imaged. One or more additional regions of the body may then be imaged to create data that may be used to estimate the input function. One or more parameters may then be estimated from each additional region of the body based on the input function and the imaging data gathered from each region.

Claims14

Dependent claims

A system for imaging at least two volumes of a patient, the system comprising:

one or more imager configured to image one volume of a patient to be imaged;
at least one patient support configured to move the patient between a first position within the one or more imager for determining an input function and at least one second position within the one or more imager for scanning at least one second volume of the patient, wherein the first volume is different than the second volume;
one or more control system comprising one or more computer;
one or more user interface;
and
an injector configured to administer at least one controlled dose of one or more tracer when the patient is in at least the first position and optionally at least one of the at least one second position;
wherein the one or more control system uses an image derived input function from the first volume to determine at least kinetic parameters for the scanning of the at least one second volume of the patient to provide a reconstructed image of the at least two volumes of the patient.

4 more elements

Dependencies are inferred from the claim text.

Facts

Application: 15/254,319Filed 1 Sep 2016 · division
Priority: 3 Jun 2011
Published: US 2017/0027539 A12 Feb 2017
Granted: 16 Jan 2018
Term ends: Not estimatedThe source records don’t support an estimate.

Classification32 codes

G16H 20/17
Relating to drugs or medications, e.g. for ensuring correct administration to patients: delivered via infusion or injection
A61B 5/055
Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves:…
A61B 5/704
Means for positioning the patient in relation to the detecting, measuring or recording means: tables
A61B 6/032
Computed tomography [CT]: transmission computed tomography [CT]

Family

Application61/493,142Us provisional application · filed 3 Jun 2011
Application61/629,414Us provisional application · filed 18 Nov 2011
PCT/US2012/040755Parent of this division · filed 4 Jun 2012
US 2017/0027539 A1Pre-grant publication · published 2 Feb 2017
Application14/123,390Parent of this division
US 9,436,989 B2Parent of this division
US 2014/0119621 A1Published application
US 9,867,589 B2This patent

From the US filing history. Foreign family members aren’t listed.