Accelerating muscle recovery after immobilization-induced muscle atrophy
AssigneeNestec S.A.
InventorsDominique Dardevet, Isabelle Savary-Auzeloux, Didier Remond, Lydie Combaret, Gary Williamson, Magali Faure, Denis Breuille
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Abstract
The present invention generally relates to the field of medical nutrition. For example, the present invention provides a composition that can be used to treat, prevent and/or reverse muscle atrophy related to immobilization and its consequences. One embodiment of the present invention concerns a composition comprising a leucine and antioxidants that can be used in accelerating muscle recovery after muscle atrophy.
Claims20
A method for the treatment of muscle atrophy caused by immobilization and not associated with aging, the method comprising:
- administering a first composition to an individual in need thereof, the first composition is administered to the individual daily for a first time period extending from when the immobilization ends to at least 14 consecutive days after the immobilization ends, the first composition comprising leucine in an amount between 2 and 10 weight-% based on total dry weight of the first composition, about 10-50 g isoleucine per kg of the first composition, about 10-50 g valine per kg of the first composition, and at least one antioxidant comprising 0.5 to 1.5 g hesperetine-7-glucoside per kg of the first composition and 1 to 2 g curcumin per kg of the first composition;
- and
- administering a second composition to the individual, the second composition is administered to the individual daily during a second time period starting when the first time period ends, the second composition comprising leucine in an amount between 2 and 10 weight-% based on total dry weight of the second composition, about 10-50 g isoleucine per kg of the second composition, and about 10-50 g valine per kg of the second composition, and at least one of the first and second compositions has at least one different ingredient relative to the other composition.
Dependencies are inferred from the claim text.