ETP derivatives

A compound having formula:

• wherein:
• p is 2;
• X1 is CR21R21A, O, NR21A, or S;
• X2 is CR22R22A, O, NR22A, or S;
• R1 is hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33A, —NR34AR35A, —COOR33A, —CONR34AR35A, —NO2, —SR36A, —SOn1R34A, —SOn1OR34A, —SOn1NR34AR35A, —NHNR34AR35A, —ONR34AR35A, —NHC(O)NHNR34AR35A, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R2 is hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33B, —NR34BR35B, —COOR33B, —CONR34BR35B, —NO2, —SR36B, —SOn2R34B, —SOn2OR34B, —SOn2NR34BR35B, —NHNR34BR35B, —ONR34BR35B, —NHC(O)NHNR34BR35B, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R3 is hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33C, —NR34CR35C, —COOR33C, —CONR34CR35C, —NO2, —SR36C, —SOn3R34C, —SOn3OR34C, —SOn3NR34CR35C, —NHNR34CR35C, —ONR34CR35C, —NHC(O)NHNR34CR35C, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R4 is hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33D, —NR34DR35D, —COOR33D, —CONR34DR35D, —NO2, —SR36D, —SOn4R34D, —SOn4OR34D, —SOn4NR34DR35D, —NHNR34DR35D, —ONR34DR35D, —NHC(O)NHNR34DR35D, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R5 is hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33E, —NR34ER35E, —COOR33E, —CONR34ER35E, —NO2, —SR36E, —SOn5R34E, —SOn5OR34E, —SOn5NR34ER35E, —NHNR34ER35E, —ONR34ER35E, —NHC(O)NHNR34ER35E, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R6 is hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33F, —NR34FR35F, —COOR33F, —CONR34FR35F, —NO2, —SR36F, —SOn6R34F, —SOn6OR34F, —SOn6NR34FR35F, —NHNR34FR35F, —ONR34FR35F, —NHC(O)NHNR34FR35F, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R7 is hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33I, —NR34IR35I, —COOR33I, —CONR34IR35I, —NO2, —SR36I, —SOn9R34I, —SOn9OR34I, —SOn9NR34IR35I, —NHNR34IR35I, —ONR34IR35I, —NHC(O)NHNR34IR35I, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R10 and R11 are independently hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33L, —NR34LR35L, —COOR33L, —CONR34LR35L, —NO2, —SR36L, —SOn12R34L, —SOn12OR34L, —SOn12NR34LR35L, —NHNR34LR35L, —ONR34LR35L, —NHC(O)NHNR34LR35L, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl, or are optionally joined together to form a substituted or unsubstituted cycloalkyl, a substituted or unsubstituted heterocycloalkyl, a substituted or unsubstituted aryl, or a substituted or unsubstituted heteroaryl;
• R12 and R13 are independently hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33M, —NR34MR35M, —COOR33M, —CONR34MR35M, —NO2, —SR36M, —SOn13R34M, —SOn13OR34M, —SOn3R34MR35M, —NHNR34MR35M, —ONR34MR35M, —NHC(O)NHNR34MR35M, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R21, R21A, R22 and R22A are independently hydrogen, halogen, —N3, —CF3, —CCl3, —CBr3, —CI3, —CN, —CHO, —OR33M, —NR34MR35M, —COOR33M, —CONR34MR35M, —NO2, —SR36M, —SOn13R34M, —SOn13OR34M, —SOn13NR34MR35M, —NHNR34MR35M, —ONR34MR35M, —NHC(O)NHNR34MR35M, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• and
• R33A, R34A, R35A, R36A, R33B, R34B, R35B, R36B, R33C, R34C, R35C, R36C, R33D, R34D, R35D, R36D, R33E, R34E, R35E, R36E, R33F, R34F, R35F, R36F, R33I, R34I, R35I, R36I, R33L, R34L, R35L, R36L, R33M, R34M, R35M, and R36M are independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• and
• n1, n2, n3, n4, n5, n6, n9, n12, and n13 are independently 1 or 2.