Hybrid ion source, mass spectrometer, and ion mobility device

A hybrid ion source, comprising:

• a chamber;
• a first ion source to generate first ions and to spray droplets or a gas component of a sample solution for ionization;
• a second ion source to generate second ions by ionizing the droplets or the gas component sprayed from the first ion source;
• and
• an aperture electrode disposed to introduce the first and second ions generated by the respective first and second ion sources to outside the chamber;
• wherein the second ion source includes:
• an opening between a first ionization area, in which the first ions are generated, and a second ionization area, in which the second ions are generated, to introduce the droplets or the gas component into the second ionization area and to emit the second ions from the second ion source, and
• first exhaust means for generating an air flow in a direction from the first ionization area towards the second ionization area,
• wherein the first ion source includes a capillary electrode to spray the droplets or the gas component of the sample solution,
• wherein the second ion source includes a needle electrode disposed at a position opposite the opening, and
• wherein the hybrid ion source further includes:
• at least one of a first power source to apply a first voltage to the capillary electrode and a second power source to apply a second voltage to the needle electrode in the second ion source;
• and
• a controller that controls a flow rate for exhaust of the first exhaust means in synchronization with a timing to switch at least one of the applied first and second voltages at the at least one of the first and the second power sources.