Artificial hollow biological tissue network and method for preparation thereof

A self-supporting network for replacement of a living tissue, said network is an artificial hollow biological tissue network comprising a plurality of elongate longitudinal multicellular aggregates arranged in a plurality of bioprinted layers which are located on top of one another, further comprising an inner surface and an outer surface, wherein

• at least one of said bioprinted layers is in shape of a planar closed loop such that a conduit for conveying fluids is defined by such bioprinted layer, and
• said longitudinal multicellular aggregate is a mixture of at least two cell types;
• further wherein said network is a branched conduit comprising at least two branches converged on at least one sector of said network;
• provided that the network comprises a branch which is out of plane with respect to the other branches of the network when the network is laid on a planar surface.