Concentration calculation system of optically active substance, manufacturing method of concentration calculation system of optically active substance, and computer readable medium

A method of calculating a concentration of an optically active substance, the method comprising:

• irradiating a measurement target including a plurality of optically-active substances with linear polarized light of different wavelengths;
• for each wavelength, measuring an optical rotation of a polarization plane after the irradiated light passes through the measurement target;
• accessing a formula representing optical rotation, the formula including:
• a first function that represents wavelength dependence of an optical rotation in the first optically-active substance of the plurality of optical substances, in which:
• (1) a concentration of the first optically-active substance has an unknown value, and (2) at least one inherent value for defining a characteristic of optical rotatory dispersion of the first optically-active substance is a known value or an unknown value within a certain limited range;
• and
• a second function that represents wavelength dependence of an optical rotation in at least one second optically-active substance of the plurality of optical substances, in which at least one inherent value for defining a characteristic of optical rotatory dispersion of the second optically-active substance is an unknown value;
• calculating the concentration of the first optically-active substance based on the accessed formula and the measured optical rotations for each wavelength, by using a least-squares method;
• and
• displaying the calculated concentration on a display.

A non-transitory computer readable medium storing a program to cause a computer to execute a function of calculating concentration of an optically active substance, the program comprising:

• instructions for irradiating a measurement target including a plurality of optically-active substances with linear polarized light of different wavelengths;
• and
• instructions for measuring, for each wavelength, an optical rotation of a polarization plane after the irradiated light passes through the measurement target;
• instructions for accessing a formula representing an optical rotation, the formula including:
• a first function representing wavelength dependence of an optical rotation of at least one first optically-active substance of the plurality of optical substances, in which:
• (1) a concentration of the first optically-active substance has an unknown value, and (2) at least one inherent value for defining a characteristic of optical rotatory dispersion of the first optically-active substance is a known value or an unknown value within a certain limited range;
• and
• a second function representing wavelength dependence of an optical rotation of at least one second optically-active substance of the plurality of optical substances, in which at least one inherent value for defining a characteristic of optical rotatory dispersion of the second optically-active substance is an unknown value;
• instructions for calculating the concentration of the first optically-active substance based on the accessed formula and the measured optical rotations for each wavelength, by using a least-squares method;
• and
• instructions for displaying the calculated concentration on a display.