Method for producing alpha-glucosidase inhibitors utilizing Paenibacillus sp
AssigneeTamkang University
InventorsSan-Lang Wang, Yao-Haur Kuo, Po-Hao Shih, Van-Bon Nguyen, Anh-Dzung Nguyen
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Abstract
A method for producing alpha-glucosidase inhibitors utilizing Paenibacillus sp., wherein utilizing a Paenibacillus sp. strain which is deposited at Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH (DSMZ) and numbered No. DSM 32521 to produce the alpha-glucosidase inhibitors, the Paenibacillus sp. Strain is cultivated in a commercial culture medium or a shrimp/crab residue-contained culture medium, and the alpha-glucosidase inhibitors is separated from a fermented supernatant. The alpha-glucosidase inhibitors have strong inhibitory activity.
Claims4
Method for producing alpha-glucosidase inhibitor utilizing Paenibacillus sp. comprising a Paenibacillus sp. strain which is a DSM 32521 strain deposited at Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures (DSMZ), and is used for production, wherein the DSM 32521 strain is cultivated under 25° C. to 37° C. for at least three days, and then is centrifuged using a rotation speed of 4000 rpm to 10000 rpm to acquire a supernatant which has alpha-glucosidase inhibitor, and wherein a carbon/nitrogen source to cultivate the DSM 32521 strain is 100 ml of 0.8% nutrient broth-contained culture medium.
Dependencies are inferred from the claim text.