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US 9,850,476 B2Granted
Degradable clostridial toxins
AssigneeAllergan, Inc.
InventorsLance E. Steward, Sanjiv Ghanshani, Ester Fernandez-Salas, Marcella A. Gilmore, Joseph Francis, Kei Roger Aoki
Life of this patent
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Abstract
The specification discloses Clostridial toxins or Clostridial toxin chimeras comprising an inactivation cleavage site, polynucleotide molecules encoding such toxins or chimeras, compositions comprising such toxins or chimeras, and method of producing such toxins or chimeras.
Claims1
A non-naturally occurring Clostridial toxin comprising SEQ ID NO:
- 537;
- wherein the non-naturally occurring Clostridial toxin comprises an inactivation cleavage site not present in a naturally occurring Clostridial toxin.
Dependencies are inferred from the claim text.