Methods of using T4 bacteriophage in treatment of adenoviral infections caused by HAdV-5
AssigneesWarszawski Uniwersytet Medyczny, Instytut Immunologii I Terapii Doswiadczalnej im. Ludwika Hirszfelda PAN we Wroclawiu
InventorsRenata Jakubowska-Zahorska, Maciej Przybylski, Jan Borysowski, Andrzej Gorski, Beata Weber-Dabrowska
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Abstract
We disclose the use of a strain of bacteriophages in the manufacturing of a preparation for improving the state of health of patients infected with adenoviruses, wherein preferably the preparation produced is used for the treatment or prevention of adenoviral infections, particularly those caused by HAdV, preferably HAdV-5.
Claims3
A method for improving the state of health of patients infected with adenovirus HadV-5, comprising providing a T4 phage preparation comprising an effective amounts of T4 phage to inhibit the proliferation of adenovirus HadV-5 by 50%, and administering the preparation to the patients in need thereof, wherein the T4 phage titers in said preparation range from about 1.47×109 to 1.47×103 PFU/ml.
A method of treating a HadV-5 adenoviral infection in a mammal in need thereof comprising administering to said mammal an effective amount of a preparation comprising T4 bacteriophage strain.
Dependencies are inferred from the claim text.