Hybridoma clones and monoclonal antibodies to tetraspanin 8
AssigneeThe Translational Genomics Research Institute
InventorDavid Azorsa
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Abstract
The present invention is directed to a monoclonal antibody that recognizes human TSPAN8 in its native form. The invention is also directed to a hybridoma cell line that produces the monoclonal antibody, and exosome purification kits using the antibody.
Claims19
A monoclonal antibody that binds to a human TSPAN8 protein, wherein the monoclonal antibody is produced by hybridoma cell line BT-43, ATCC accession number PTA-121023.
An isolated monoclonal antibody produced by hybridoma cell line BT-43, ATCC accession number PTA-121023.
A method of making a monoclonal antibody, the method comprising providing hybridoma cell line BT-43, ATCC accession number PTA-121023, which produces a monoclonal antibody specific for human tetraspanin 8, and culturing the hybridoma cell line BT-43 under conditions that permit the production of the monoclonal antibody.
An exosome purification kit comprising at least one container containing a monoclonal antibody produced by a hybridoma cell line of BT-43, ATCC accession number PTA-121023.
Dependencies are inferred from the claim text.