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US 9,850,237 B2Granted
Orexin receptor antagonists
AssigneeHeptares Therapeutics Limited
InventorsMiles Stuart Congreve, John Andrew Christopher, Benjamin Gerald Tehan, Sukhbinder Singh Klair, Sarah Joanne Aves
Life of this patent
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Abstract
The disclosures herein relate to novel compounds of formula wherein W, X and Y1, Y2, Y3 and Y4 are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of neurological or psychiatric disorders associated with orexin receptors.
Claims12
A compound of formula
- Wherein:
- (i) Y1, Y2, Y3 and Y4 are independently a carbon or a nitrogen atom, wherein no more than one of Y1, Y2, Y3 and Y4 is a nitrogen atom;
- (ii) W is selected from:
- and
- (iii) X is selected from:
2 more elements
Dependencies are inferred from the claim text.