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US 9,850,195 B2Granted
Aspirin derivatives and uses thereof
AssigneeNorth Carolina Agricultural and Technical State University
InventorShengmin Sang
Life of this patent
Estimating the term…
Abstract
The present invention provides novel aspirin derivatives useful for preventing and/or treating cancer. The novel compounds of this invention may be particularly useful for the prevention and/or treatment of cancers affecting the gastrointestinal system, such as colorectal cancer.
Claims14
A method of treating colorectal cancer in a subject in need thereof, comprising:
- administering to said subject a therapeutically effective amount of the following compound:
- or a pharmaceutically acceptable salt thereof,
- wherein:
- RE is —O—C(O)—C1-3alkyl;
- RF is
- or
- wherein n=3, 5, or 7;
- and
- RG is —H or C1-6 alkyl.
6 more elements
A method of treating lung cancer in a subject in need thereof, comprising:
- administering to said subject a therapeutically effective amount of the following compound:
- or a pharmaceutically acceptable salt thereof,
- wherein:
- RE is —O—C(O)—C1-3alkyl;
- RF is
- or
- wherein n=3, 5, or 7;
- and
- RG is —H or C1-6 alkyl.
6 more elements
Dependencies are inferred from the claim text.