Glass packaging ensuring container integrity
AssigneeCorning Incorporated
InventorsSteven Edward DeMartino, Robert Anthony Schaut
Life of this patent
Estimating the term…
Abstract
A strengthened glass container or vessel such as, but not limited to, vials for holding pharmaceutical products or vaccines in a hermetic and/or sterile state. The strengthened glass container undergoes a strengthening process that produces compression at the surface and tension within the container wall. The strengthening process is designed such that the tension within the wall is great enough to ensure catastrophic failure of the container, thus rendering the product unusable, should sterility be compromised by a through-wall crack. The tension is greater than a threshold central tension, above which catastrophic failure of the container is guaranteed, thus eliminating any potential for violation of pharmaceutical integrity.
Claims73
A container comprising a glass, the container having a thickness and a first surface and a second surface, wherein the glass is an ion exchanged aluminosilicate glass comprising at least one alkali metal oxide, the glass having a first region under a compressive stress, the first region extending from at least one of the first surface or the second surface to a depth of layer in the glass, and a second region under a central tension, the second region extending from the depth of layer, wherein the central tension is greater than or equal to about 15 MPa, the glass has a Young's modulus E and a Poisson's ratio ν, and (CT2/E)·(t−2DOL)·(1−ν)≧3.0 MPa·μm, where CT is the central tension, t is the thickness, and DOL is the depth of layer, and the first region comprises a coating having a Young's modulus different than the glass.
A glass article having a first surface and a second surface separated by glass having a thickness, wherein the glass is an ion exchanged aluminosilicate glass comprising at least one alkali metal oxide and the glass article has a first region under a compressive stress, the first region extending from at least one of the first surface or the second surface to a depth of layer in the glass, and a second region under a central tension of at least about 15 MPa, the second region extending from the depth of layer, wherein the first region comprises a coating having a Young's modulus different than the glass, the central tension is sufficient to allow self-propagation of a crack front from the first surface to the second surface and laterally across the first surface, and the glass article is a container adapted to hold a pharmaceutical product, a vaccine, a biologic, a foodstuff, or a solution.
A container comprising a glass, the container having a thickness and a first surface and a second surface, wherein the glass is an ion exchanged aluminosilicate glass comprising at least one alkali metal oxide and has a first region under a compressive stress, the first region extending from at least one of the first surface or the second surface to a depth of layer in the glass, and a second region under a central tension, the second region extending from the depth of layer, and the glass has a Young's modulus E and a Poisson's ratio ν, wherein (CT2/E)·(t−2DOL)·(1−ν)≧3.0 MPa·μm, where CT is the central tension, t is the thickness, and DOL is the depth of layer, and the first region comprises a coating having a Young's modulus different than the glass.
A container comprising a glass, the container having a thickness of from 1 mm to 1.2 mm and a first surface and a second surface, wherein the glass is an ion exchanged aluminosilicate glass comprising at least one alkali metal oxide, the glass having a first region under a compressive stress, the first region extending from at least one of the first surface or the second surface to a depth of layer in the glass, and a second region under a central tension, the second region extending from the depth of layer, wherein the central tension is greater than 22 MPa and the glass has a Young's modulus E and a Poisson's ratio ν, and (CT2/E)·(t−2DOL)·(1−ν)≧3.0 MPa·μm, where CT is the central tension, t is the thickness, and DOL is the depth of layer.
A glass article having a first surface and a second surface separated by glass having a thickness of from 1 mm to 1.2 mm, wherein the glass is an ion exchanged aluminosilicate glass comprising at least one alkali metal oxide and the glass article has a first region under a compressive stress, the first region extending from at least one of the first surface or the second surface to a depth of layer in the glass, and a second region under a central tension greater than 22 MPa, the second region extending from the depth of layer, wherein the central tension is sufficient to allow self-propagation of a crack front from the first surface to the second surface and laterally across the first surface, and the glass article is a container adapted to hold a pharmaceutical product, a vaccine, a biologic, a foodstuff, or a solution.
Dependencies are inferred from the claim text.