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US 9,849,611 B2Granted
Method for producing collagen-containing sheet material
AssigneeAap Biomaterials GmbH
InventorsMarco Wolfstaedter, Birgit Schaefer, Ellen Schubert
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Abstract
A method for producing a collagen-containing sheet material, wherein a collagen-containing suspension is dried in such a manner that the collagen settles during drying and forms a transparent skin.
Claims8
A method for producing a collagen-containing sheet material, comprising:
- treating a mammalian skin starting material with wet chemicals;
- mechanically comminuting the treated starting material into a slurry;
- preparing an aqueous suspension of the comminuted, treated starting material from the slurry, said aqueous suspension having a solid content from 0.5 to 5%;
- adjusting the pH of the aqueous suspension to a pH between 5.5 and 8;
- transferring the aqueous suspension to a tray;
- waiting until at least a portion of the suspension in the tray settles out before drying;
- and
- drying the aqueous suspension in the tray such that a transparent film of the collagen-containing sheet material is formed having a closed porosity of less than 20%;
- wherein said collagen-containing sheet material comprises more than 70% of collagen;
- and
- wherein said collagen-containing sheet material has a thickness between 0.05 and 2 mm.
8 more elements
Dependencies are inferred from the claim text.