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US 9,849,456 B2Granted
Microfluidic device
AssigneeClearbridge Mfluidics Pte. Ltd.
InventorSwee Jin Tan
Life of this patent
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Abstract
Disclosed herein is a microfluidic device comprising, at least one sample inlet for receiving biological cells in a biological fluid sample; at least one sheath flow inlet for receiving a sheath fluid; at least one curvilinear channel configured to provide the biological fluid sample substantially in an outer flow and the sheath fluid in substantially an inner separated flow; a plurality of cell traps at the periphery of the curvilinear channel, each trap configured to admit a single cell having a targeted size range from the outer flow.
Claims19
A microfluidic device comprising:
- at least one sample inlet for receiving biological cells in a biological fluid sample;
- at least one sheath flow inlet for receiving a sheath fluid;
- at least one curvilinear channel defining an arc region configured to provide the biological fluid sample substantially in a stable outer layer flow and the sheath fluid in substantially a stable inner layer separated flow;
- and
- a plurality of cell traps at the periphery of the arc region of the curvilinear channel, each trap configured to admit a single cell having a targeted size range from the outer layer flow.
2 more elements
Dependencies are inferred from the claim text.