Method for preparation of pharmaceutical products

A method for preparation of pharmaceutical products, the method comprising:

• a) providing a machine (1) for preparing at least one pharmaceutical product via at least one dosing chamber (2) provided with a mixing assembly (13) and a pneumatic ventilation device (31), wherein the machine (1) further comprises a containing liner (27) that extends about the dosing chamber (2) so as to define a first containing chamber (23, 30) and a second containing chamber (16) for a store (14) for a plurality of containers (15) containing at least one of pharmaceutical product and diluents therein;
• b) generating air flow via the pneumatic ventilation device (31), wherein a first air flow is directed into the dosing chamber (2) and at least one second air flow is directed into the containing liner (27);
• c) selectively controlling the pneumatic ventilation device (31) with a control unit (54), wherein said control unit (54) controls the pneumatic ventilation device (31) so as to control the first and second air flows, so that the containing liner (27) has inside a pressure lower than a pressure existing within the dosing chamber (2) and a pressure lower than a pressure existing in the environment outside the containing liner (27) itself;
• d) feeding the first air flow through the dosing chamber (2) via a first feeding circuit (33);
• e) aspirating the second air flow from the first containing chamber (23, 30) via a second feeding circuit (45);
• f) feeding a third air flow through the second containing chamber (16) via a third feeding circuit (48);
• g) providing a loading station (56) of the containers (15) into the store (14) and at least one communication door for connecting the store (14) and the environment outside the containing liner (27) to each other;
• and
• h) feeding a fourth air flow from the pneumatic ventilation device (31) along and external to said at least one communication door via a fourth feeding circuit (55), wherein said fourth air flow is external to the containing liner (27) and obstructs introduction of air from the environment outside the containing liner (27).