Applicator

An applicator for applying a microneedle sheet to skin, comprising:

• a sheet-like body having a bottom surface facing the skin, a top surface, a longitudinal direction and an orthogonal, width-wise direction;
• a slit-shaped first through hole positioned in the orthogonal direction of the sheet-like body;
• a slit-shaped second through hole positioned in the orthogonal direction opposite the first through hole;
• and
• a rectangular adhesive layer provided on the bottom surface of the sheet-like body and surrounding the first and second through holes,
• wherein the microneedle sheet comprises a plurality of microneedles extending along a main surface of the microneedle sheet and the main surface of the microneedle sheet is covered with a liner,
• wherein when the liner with the microneedle sheet is inserted in the applicator through the first through hole, the microneedle sheet is bent 180 degrees and fixed to the adhesive layer of the applicator adjacent thereto, and the applicator and microneedle sheet and liner are affixed to the skin and the liner is moved in the longitudinal direction of the applicator so the microneedle sheet separates from the liner thereby raising at least one microneedle from the main surface of the microneedle sheet, the at least one raised microneedle sticks into the skin, and the second through hole guides the liner away from the skin.