Low dose prefilled drug delivery device and method

A drug delivery device for administering a low dose of a medicament, comprising:

• a housing having a needle hub with a fluid outlet channel;
• a drug reservoir disposed in said housing and containing a medicament, said drug reservoir having a seal formed from a layer that is ruptured by applying a dispensing pressure to said drug reservoir, said drug reservoir having an outlet passage extending between said seal and said fluid outlet channel in said needle hub;
• a needle connected to said housing and having a first end in communication with said drug reservoir and a second end extending outwardly from said needle hub, said fluid outlet channel communicating with said drug reservoir, and said needle having an end received in said outlet passage of said drug reservoir and spaced from said seal;
• and
• a pressure applying member movably connected to said housing and movable between first and second positions with respect to said drug reservoir, said pressure applying member not applying pressure to said drug reservoir in said first position and contacting and applying the dispensing pressure to said drug reservoir in said second position rupturing said seal and dispensing said medicament stored in said drug reservoir through said needle, said first end of said needle being spaced from said seal of said drug reservoir defining a gap between said needle and said seal of said drug reservoir when said pressure applying member is in said first position and said needle being spaced from said seal of said drug reservoir defining the gap between said needle and seal of said drug reservoir when said pressure applying member is in said second position.