Data modification for predictive operations and devices incorporating same

An infusion system comprising:

• a sensing arrangement to obtain a sequence of measurements of a condition in a body of a user, identify one or more unusable measurements in the sequence of measurements, modify a value for the one or more unusable measurements in the sequence to obtain a modified sequence of measurements, determine an estimate of a trend in the sequence of measurements based at least in part on differences between consecutive measurements of the modified sequence of measurements, determine a predicted value for the condition in the body of the user at a time in the future based at least in part on the estimate of the trend and a current measurement of the condition, and transmit the predicted value and the current measurement of the condition, wherein:
• the sensing arrangement includes a sensing element providing a signal indicative of the condition;
• the one or more unusable measurements are replaced in the modified sequence with an interpolated value based on a preceding usable measurement in the sequence and a succeeding usable measurement in the sequence when a number of measurement samples corresponding to a gap between the preceding usable measurement and the succeeding usable measurement is less than an interpolation threshold;
• and
• the one or more unusable measurements are backfilled with the succeeding usable measurement when the number of measurement samples corresponding to the gap is greater than the interpolation threshold;
• and
• an infusion device to receive the predicted value and the current measurement, the infusion device including:
• a motor operable to deliver fluid to the body of the user;
• and
• a control module coupled to the motor to operate the motor based at least in part on the current measurement in a manner that is influenced by the predicted value.