Generation and application of an insulin limit for a closed-loop operating mode of an insulin infusion system

A tangible and non-transitory electronic storage medium having processor-executable instructions that, when executed by a processor architecture comprising at least one processor device, perform a method of controlling closed-loop delivery of insulin from an insulin reservoir of an insulin infusion device to a user, the method comprising:

• calculating a maximum insulin infusion rate for the user based on a fasting blood glucose value associated with the user, a total daily insulin value associated with the user, and fasting insulin delivery data that is indicative of insulin delivered to the user during a fasting period, wherein the maximum insulin infusion rate is applicable during a period of closed-loop operation of the insulin infusion device;
• obtaining a first closed-loop insulin infusion rate for the user, wherein the first closed-loop insulin infusion rate is obtained for a current sampling point during the period of closed- loop operation;
• providing a second closed-loop insulin infusion rate for the user when the obtained first closed-loop insulin infusion rate is greater than the calculated maximum insulin infusion rate, wherein the second closed-loop insulin infusion rate is less than the first closed-loop insulin infusion rate;
• and
• operating the insulin infusion device in a closed-loop mode to continuously deliver insulin from the insulin reservoir to the user in accordance with either the first closed-loop insulin infusion rate or the second closed-loop insulin infusion rate.

An electronic controller for an insulin infusion device having an insulin reservoir, the electronic controller comprising:

• a processor architecture comprising at least one processor device;
• and
• at least one memory element associated with the processor architecture, the at least one memory element storing processor-executable instructions that, when executed by the processor architecture, provide a closed-loop insulin limit module configured to:
• obtain a fasting blood glucose value associated with the user, the fasting blood glucose value corresponding to a fasting period for the user;
• obtain a total daily insulin value associated with the user;
• obtain fasting insulin delivery data that is indicative of insulin delivered to the user during the fasting period;
• calculate a maximum insulin infusion rate for the user based on the obtained fasting blood glucose value, the obtained total daily insulin value, and the obtained fasting insulin delivery data, wherein the maximum insulin infusion rate is applicable during a period of closed-loop operation of the insulin infusion device;
• and
• operating the insulin infusion device in a closed-loop mode to continuously deliver insulin from the insulin reservoir to the user in accordance with the maximum insulin infusion rate.