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US 9,849,215 B2Granted
Implantable compositions and methods for preparing the same
AssigneeWarsaw Orthopedic, Inc.
InventorsChristina Mossaad, Lawrence A. Shimp, Guobao Wei, John Winterbottom
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Abstract
Methods for forming implantable compositions are provided. In some embodiments, the methods include (i) providing a gel base, (ii) adding water and a hydrating agent to the gel base to form a mixture, (iii) reducing the water content of the mixture; and (iv) adding a delivered material before, during, and/or after step (ii) or (iii). The water content is reduced to about 5% or less by weight of the implantable composition.
Claims19
A method for preparing an implantable composition comprising:
- (i) providing a gel base comprising dextran;
- (ii) adding water, anhydrous citric acid and a hydrating agent to the gel base to form a mixture;
- (iii) reducing the water content of the mixture;
- and (iv) adding a delivered material before, during, and/or after step (ii) or (iii);
- wherein the water content is reduced to about 5% or less by weight of the implantable composition.
2 more elements
An implantable composition comprising:
- a delivered material, and a carrier comprising:
- a gel base comprising dextran;
- anhydrous citric acid;
- and a hydrating agent;
- wherein a water content of the implantable composition is less than about 5% by weight of the composition.
2 more elements
Dependencies are inferred from the claim text.