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US 9,849,183 B2Granted
Compound prescription colloidal eyedrop gel and methods of making the same
AssigneeNational Chiao Tung University
InventorsDean-Mo Liu, Yi-Ling Wang
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Abstract
The present disclosure herein provides a compound prescription colloidal eyedrop gel. The compound prescription colloidal eyedrop gel includes a plurality of carboxymethyl-hexanoyl chitosan (CHC) micelles, a basic structural stabilizer connecting the plurality of CHC micelles, a first drug inside the CHC micelle, and a second drug outside the CHC micelle.
Claims11
A compound prescription colloidal eyedrop gel, comprising:
- a plurality of carboxymethyl-hexanoyl chitosan (CHC) micelles, wherein each of the CHC micelles has an inner hydrophobic layer and an outer hydrophilic layer;
- a basic structural stabilizer connecting the plurality of CHC micelles;
- a first drug inside the CHC micelle, wherein the first drug is a water-soluble drug;
- and
- a second drug outside the CHC micelle, wherein the second drug is a lipid-soluble drug.
2 more elements
Dependencies are inferred from the claim text.