PRRSV compositions
AssigneeRegents of the University of Minnesota
InventorHan-Soo Joo
Life of this patent
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Abstract
This invention provides kits, devices, and methods for the detection of antibodies that recognize one or more proteins and/or antigens from porcine reproductive and respiratory syndrome virus (PRRSV). The antibodies may be in a biological fluid of a PRRSV infected or at risk subject. The invention may be advantageously applied to both the diagnosis and prevention of PRRSV infection.
Claims21
A vaccine composition, comprising PRRS virus polypeptides, virus-infected cell lysate, a detergent, and an adjuvant.
A vaccine composition, comprising:
- cell-associated PRRS virus proteins and antigens, comprising PRRS virus envelope proteins, a PRRS virus N protein, a PRRS virus encoded glycoprotein, or a combination thereof, the cell-associated PRRS virus proteins and antigens being isolated from PRRS virus infected cells;
- PRRS virus-infected cell lysate comprising cellular components;
- a non-ionic detergent;
- and
- an adjuvant.
A method of generating an immune response in a swine, comprising administering to the swine a vaccine composition comprising PRRS virus polypeptides, virus-infected cell lysate, a detergent, and an adjuvant.
Dependencies are inferred from the claim text.