MDR E. coli specific antibody
AssigneeArsanis Biosciences GmbH
InventorsEszter Nagy, Gábor Nagy, Valéria Szijárto, Zoltán Magyarics, Irina Mirkina, Luis Guachalla, Adriana Badarau, Gerhild Zauner, Jolanta Lukasiewicz
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Abstract
The subject relates to an isolated antibody that specifically binds to O25b antigen of multi drug resistant (MDR) E. coli strains, its medical and diagnostic use, method of producing the antibody, including an isolated nucleotide sequence, plasmids and host cells as used in the production of the antibody; and further an isolated epitope recognized the specific antibody.
Claims5
A monoclonal antibody composition comprising:
- an isolated monoclonal antibody that specifically binds to 025b antigen of multi drug resistant (MDR) E. coli strains, and
- a carrier or excipient.
A monoclonal antibody composition comprising:
- a) an isolated monoclonal antibody that specifically binds to 025b antigen of multi drug resistant (MDR) E. coli strains which comprises:
- the variable region of the antibody light chain produced by the host cell deposited under DSM 26763;
- and
- the variable region of the antibody heavy chain produced by the host cell deposited under DSM 26762;
- and
- b) a carrier or excipient.
A monoclonal antibody composition comprising:
- a) an isolated monoclonal antibody that specifically binds to 025b antigen of multi drug resistant (MDR) E. coli strains which comprises:
- the variable region of the antibody light chain produced by the host cell deposited under DSM 28171;
- and
- the variable region of the antibody heavy chain produced by the host cell deposited under DSM 28172;
- and
- b) a carrier or excipient.
Dependencies are inferred from the claim text.